I'm by no means an expert, but from my experience you would need to identify the plays that meet your desired lineup, determine if it contains Goaline, Normal, Nickel, Dime or Quarter. Then adjust the sliders to favor that personnel configuration. Then adjusting the Secondary and Linebacker settings so they favorably match the plays you would like called.
This is not an exact science, but you can get pretty close. You can always adjust your settings and then "view plays" to bring up all the plays from which the coaches will decide.